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Domestic Animal Endocrinology
Volume 39, Issue 4
, Pages 222-230
, November 2010
Effect of hyperlipidemia on 11β-hydroxysteroid-dehydrogenase, glucocorticoid receptor, and leptin expression in insulin-sensitive tissues of cats
References
- . Obesity and gender influence cortisol secretion and metabolism in man. J Clin Endocrinol Metab. 1998;83:1806–1809
- . 11β-hydroxysteroid dehydrogenase type 1 in obesity and type 2 diabetes. Diabetologia. 2004;47:1–11
- . Effect of glucocorticoids on plasma insulin. N Engl J Med. 1966;274:1237–1241
- . Effects of glucocorticoids on carbohydrate metabolism. Am J Med Sci. 1976;271:202–210
- . Insulin resistance in Cushing's Syndrome. J Clin Endocrinol Metab. 1983;57:529–536
- . Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase. J Biol Chem. 1989;264:18939–18943
- . Immunohistochemical localization of type 1 11β-hydroxysteroid dehydrogenase in human tissues. J Clin Endocrinol Metab. 1998;83:1325–1335
- . Localisation of 11β-hydroxysteroid dehydrogenase – tissue specific protector of the mineralocorticoid receptor. Lancet. 1988;2:986–989
- . Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol. 1994;105:R11–R17
- . A transgenic model of visceral obesity and metabolic syndrome. Science. 2001;294:2166–2170
- . 11β-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress. Proc Natl Acad Sci U S A. 1997;94:14924–14929
- . Improved lipid and lipoprotein profile, hepatic insulin sensitivity and glucose tolerance in 11β-hydroxysteroid dehydrogenase type 1 null mice. J Biol Biochem. 2001;276:41293–41300
- . Selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice. Diabetologia. 2002;45:1528–1532
- . 11β-hydroxysteroid dehydrogenase type 1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice. J Exp Med. 2005;202:517–527
- . Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes. 2002;51:7–18
- . Relationship between inflammation, insulin resistance and type 2 diabetes: cause or effect?. Curr Diabetes Rev. 2006;2:195–211
- . Free fatty acids (FFA), a link between obesity and insulin resistance. Front Biosci. 1998;3:D169–D175
- . Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites. Am J Physiol Endocrinol Metab. 2003;284:E281–E290
- . In vivo activity of 11β-hydroxysteroid dehydrogenase type 1 and free fatty acid-induced insulin resistance. Clin Endocrinol. 2005;63:442–449
- . Acute in vivo regulation of 11β-hydroxysteroid dehydrogenase type 1 activity by insulin and intralipid infusions in humans. J Clin Endocrinol Metab. 2006;91:4682–4688
- . Pathogenesis of feline diabetes mellitus. Vet Clin North Am Small Anim Pract. 1995;25:527–552
- . Animal models of type 2 diabetes: clinical presentation and pathophysiological relevance to the human condition. ILAR J. 2006;47:186–198
- . Feline models of type 2 diabetes mellitus. ILAR J. 2006;47:234–242
- . Textbook of Veterinary Internal Medicine. 7th ed.. St. Louis, Missouri: Saunders Elsevier; 2010;
- . Hyperglycemia but not hyperlipidemia causes beta cell dysfunction and beta cell loss in the domestic cat. Diabetologia. 2009;52:336–346
- . Effect of high carbohydrate and high fat diet on plasma metabolite levels and iv glucose tolerance test in intact and neutered male cats. J Fel Med Surg. 2004;6:207–218
- . Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care. 1999;22:1462–1470
- . Quantitative real-time PCR for the measurement of feline cytokine mRNA. Vet Immunol Immunopathol. 1999;71:291–305
- . Quantitative real-time PCR for the measurement of 11β-HSD1 and 11β-HSD2 mRNA levels in tissues of healthy dogs. Horm Metab Res. 2007;39:548–554
- . Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest. 1996;97:2859–2865
- . Rapid impairment of skeletal muscle glucose transport/phosphorylation by free fatty acids in humans. Diabetes. 1999;48:358–364
- . Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes. J Clin Endocrinol Metab. 2004;89:1301–1311
- . Dose-response effect of elevated plasma free fatty acid on insulin signaling. Diabetes. 2005;54:1640–1648
- . TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest. 2006;116:3015–3025
- . Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men. Diabetologia. 2008;51:139–146
- . Local and systemic impact of transcriptional up-regulation of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue in human obesity. J Clin Endocrinol Metab. 2003;88:3983–3988
- . Mifepristone (RU486), a blocker of type II glucocorticoid and progestin receptors, reverses a dietary form of obesity. Am J Physiol. 1992;262:R1106–R1110
- . Abnormal regulation of hepatic glucocorticoid receptor mRNA and receptor protein distribution in the obese Zucker rat. Obes Res. 1996;4:133–143
- . Increased glucocorticoid receptor and 11β-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in db/db mice. Diabetes. 2005;54:32–40
- . Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism. Diabetes. 2005;54:1846–1853
- . Steroid hormone receptors in human adipose tissues. J Clin Endocrinol Metab. 1990;71:1215–1219
- . Insulin sensitivity, fat distribution, and adipocytokine response to different diets in lean and obese cats before and after weight loss. Am J Physiol Regul Integr Comp Physiol. 2007;292:R227–R234
- . Visceral fat accumulation in men is positively associated with insulin, glucose and C-peptide levels, but negatively with testosterone levels. Metabolism. 1990;39:897–901
- . Gonadal hormones determine sensitivity to central leptin and insulin. Diabetes. 2006;55:978–987
- . The effect of high-fat diet on plasma ghrelin and leptin levels in rats. J Physiol Biochem. 2009;65:157–164
- . Impact of ovariohysterectomy and food intake on body composition, physical activity, and adipose gene expression in cats. J Anim Sci. 2009;87:594–602
- . Expression of the mRNA coding for 11β-hydroxysteroid dehydrogenase type 1 in adipose tissue from obese patients: An in situ hybridization study. J Clin Endocrinol Metab. 2002;87:2701–2705
- . Tissue-specific changes in pheripheral cortisol metabolism in obese women: increased adipose 11β-hydroxysteroid dehydrogenase type 1 activity. J Clin Endocrinol Metab. 2002;87:3330–3336
PII: S0739-7240(10)00072-X
doi: 10.1016/j.domaniend.2010.06.003
© 2010 Elsevier Inc. All rights reserved.
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Domestic Animal Endocrinology
Volume 39, Issue 4
, Pages 222-230
, November 2010
